Search results for "spectrum [cosmic radiation]"

showing 10 items of 636 documents

The Greenland shark Somniosus microcephalus—Hemoglobins and ligand-binding properties

2017

A large amount of data is currently available on the adaptive mechanisms of polar bony fish hemoglobins, but structural information on those of cartilaginous species is scarce. This study presents the first characterisation of the hemoglobin system of one of the longest-living vertebrate species (392 +/- 120 years), the Arctic shark Somniosus microcephalus. Three major hemoglobins are found in its red blood cells and are made of two copies of the same a globin combined with two copies of three very similar beta subunits. The three hemoglobins show very similar oxygenation and carbonylation properties, which are unaffected by urea, a very important compound in marine elasmobranch physiology.…

---0301 basic medicinegenetic structuresProtein ConformationGreenlandlcsh:MedicineRESONANCE RAMAN-SPECTRAHETERODONTUS-PORTUSJACKSONISpectrum Analysis RamanBiochemistrychemistry.chemical_compoundHemoglobinsProtein structureAMINO-ACID SEQUENCEAnimal CellsSequence Analysis ProteinRed Blood CellsUreaNOTOTHENIOID FISHESPost-Translational Modificationlcsh:ScienceHemeChondrichthyesMultidisciplinarybiologyChemistryOrganic CompoundsChemical ReactionsVertebrateEukaryotaMOLECULAR ADAPTATIONSMicrocephalusGlobinsChemistryBiochemistryOptical EquipmentVertebratesPhysical SciencesEngineering and TechnologyCellular TypesResearch ArticleEnvironmental MonitoringProtein BindingQUATERNARY STRUCTURESAllosteric regulationEquipmentSTRETCHING FREQUENCIESHeme03 medical and health sciencesOXYGEN-BINDINGbiology.animalAnimals14. Life underwaterGlobinHemoglobinPhotolysisBlood Cells030102 biochemistry & molecular biologyLaserslcsh:ROrganic ChemistryOrganismsChemical CompoundsBiology and Life SciencesProteinsxxxCell Biologybiology.organism_classificationCARTILAGINOUS FISHOxygen030104 developmental biologySomniosusFishSharkslcsh:QHemoglobinProtein MultimerizationELASMOBRANCH HEMOGLOBINElasmobranchiiPLoS ONE
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A fully-digital realtime SoC FPGA based phase noise analyzer with cross-correlation

2017

We report on a fully-digital and realtime operation of a phase noise analyzer using modern digital techniques with cross-correlation. With the advent of system on chip field-programmable gate arrays (SoC FPGAs) embedding hard core central processing unit, coprocessor and FPGA onto a single integrated circuit, the building of sensitive analysis devices for Time & Frequency research is made accessible at virtually no cost and benefits from reconfigurability. Used with high-speed digitizers we have successfully implemented a four-channel system whose preliminary results at 10 MHz shows a residual white noise floor < −185 dBrad2/Hz up to 5 MHz off the carrier, and flicker < −127 dBrad2/Hz using…

010302 applied physicsEngineeringSpectrum analyzerNoise measurementbusiness.industryReconfigurabilityIntegrated circuitWhite noise01 natural scienceslaw.inventionlaw0103 physical sciencesPhase noiseElectronic engineeringSystem on a chipField-programmable gate arraybusiness010301 acoustics2017 Joint Conference of the European Frequency and Time Forum and IEEE International Frequency Control Symposium (EFTF/IFC)
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Development of hard x-ray photoelectron SPLEED-based spectrometer applicable for probing of buried magnetic layer valence states

2016

Abstract A novel design of high-voltage compatible polarimeter for spin-resolved hard X-ray photoelectron spectroscopy (Spin-HAXPES) went into operation at beamline BL09XU of SPring-8 in Hyogo, Japan. The detector is based on the well-established principle of electron diffraction from a W(001) single-crystal at a scattering energy of 103.5 eV. It's special feature is that it can be operated at a high negative bias potential up to 10 kV, necessary to access the HAXPES range. The polarimeter is operated behind a large hemispherical analyzer (Scienta R-4000). It was optimized for high transmission of the transfer optics. A delay-line detector (20 mm dia.) is positioned at the exit plane of the…

010302 applied physicsSpectrum analyzerRadiationPhysics - Instrumentation and DetectorsSpin polarizationSpectrometerScatteringbusiness.industryChemistryFOS: Physical sciencesPolarimeterInstrumentation and Detectors (physics.ins-det)Condensed Matter Physics01 natural sciencesAtomic and Molecular Physics and OpticsElectronic Optical and Magnetic MaterialsOpticsX-ray photoelectron spectroscopyElectron diffraction0103 physical sciencesPhysical and Theoretical Chemistry010306 general physicsSpectroscopybusinessSpectroscopy
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Mineral phase in shell repair of Manila clam Venerupis philippinarum affected by brown ring disease.

2011

14 pages; International audience; The mineral phase of shell repair in the Manila clam Venerupis philippinarum affected by brown ring disease (BRD) was characterised at various scales and at various stages of shell repair by confocal Raman microspectrometry and scanning electron microscopy. Spherulitic and quadrangular aragonite microstructures associated with polyene pigments were clearly observed. Von Kossa staining showed that at the beginning of shell repair, hemocytes are filled with insoluble calcium carbonate salts in all fluids and then are transported toward the extrapallial fluids and the repair sites. Our analyses suggest that after a Vibrio tapetis attack and BRD deposit some cl…

0106 biological sciencesBiomineralizationHemocytesMineralogyAquatic Scienceengineering.materialSpectrum Analysis Raman010603 evolutionary biology01 natural sciences03 medical and health scienceschemistry.chemical_compoundRaman microspectrometryVenerupis philippinarumAnimalsVon Kossa stain[SDV.IB.BIO]Life Sciences [q-bio]/Bioengineering/BiomaterialsMolluscaEcology Evolution Behavior and Systematics030304 developmental biologyVibrio0303 health sciencesbiologyAragoniteBivalviabiology.organism_classification[ SDV.IB.BIO ] Life Sciences [q-bio]/Bioengineering/BiomaterialsShell microstructureBivalviaCalcium carbonateAragonitechemistry[SDU]Sciences of the Universe [physics]engineeringBiophysicsCarbonateMolluscCalcium carbonateScanning electron microscopyBiomineralizationDiseases of aquatic organisms
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Spray-Drying Performance and Thermal Stability of L-Ascorbic Acid Microencapsulated with Sodium Alginate and Gum Arabic

2019

[EN] The potential of sodium alginate (ALG) and gum arabic (GA) as wall polymers for Lascorbic acid (AA) encapsulation as a tool for their preservation against the thermo-oxidative degradation was investigated. The influence of such polymers used as wall material on the AAcontent, size, encapsulation efficiency, encapsulation yield and thermo-oxidative stability were evaluated. The AA-microparticles were obtained using the spray-drying technique. An experimental Taguchi design was employed to assess the influence of the variables in the encapsulation process. The microparticles morphology and size distribution were characterized by scanning electron microscopy and laser diffraction. The the…

0106 biological sciencesfood.ingredientMaterials scienceChemical PhenomenaScanning electron microscopeAlginatesDrug Compoundinggum arabicPharmaceutical ScienceAscorbic AcidL-ascorbic acid01 natural sciencesArticleAnalytical Chemistrysodium alginatelcsh:QD241-4410404 agricultural biotechnologyfoodDifferential scanning calorimetryDrug Stabilitylcsh:Organic chemistry010608 biotechnologyDrug DiscoveryThermal stabilityspray-dryingPhysical and Theoretical ChemistryParticle Sizechemistry.chemical_classificationAnalysis of VarianceMolecular StructurenanotechnologySpectrum AnalysisOrganic ChemistryTemperature04 agricultural and veterinary sciencesPolymerAscorbic acid040401 food scienceThermogravimetrychemistryChemical engineeringChemistry (miscellaneous)Spray dryingMAQUINAS Y MOTORES TERMICOSMolecular MedicineGum arabicencapsulation
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Transformation of Construction Cement to a Self-Healing Hybrid Binder

2019

A new biomimetic strategy to im prove the self-healing properties of Portland cement is presented that is based on the application of the biogenic inorganic polymer polyphosphate (polyP), which is used as a cement admixture. The data show that synthetic linear polyp, with an average chain length of 40, as well as natural long-chain polyP isolated from soil bacteria, has the ability to support self-healing of this construction material. Furthermore, polyP, used as a water-soluble Na-salt, is subject to Na+/Ca2+ exchange by the Ca2+ from the cement, resulting in the formation of a water-rich coacervate when added to the cement surface, especially to the surface of bacteria-containing cement/c…

0211 other engineering and technologies02 engineering and technologylaw.inventionlcsh:Chemistrychemistry.chemical_compoundBiomimetic MaterialsPolyphosphateslaw021105 building & constructionComposite materiallcsh:QH301-705.5SpectroscopycoacervateCoacervatesoil bacteriaGeneral Medicine021001 nanoscience & nanotechnology6. Clean waterComputer Science Applicationsmicrocapsulessurgical procedures operative0210 nano-technologyinorganic polyphosphateManufactured MaterialsPortland cementMaterials scienceArticleCatalysisInorganic Chemistryotorhinolaryngologic diseasesself-healingPhysical and Theoretical ChemistryMolecular BiologyCementSoil bacteriaInorganic polymerConstruction MaterialsSpectrum AnalysisPolyphosphateOrganic ChemistryWaterModels Theoreticaldigestive system diseasesPortland cementlcsh:Biology (General)lcsh:QD1-999chemistrySelf-healingMicroscopy Electron ScanningHardening (metallurgy)concretemicrocracksInternational Journal of Molecular Sciences
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Mineral Profile of Children’s Fast Food Menu Samples

2017

Abstract Children’s fast food menus, including hamburgers served with french fries, dessert, and a soft drink, were analyzed to obtain the mineral profile of trace elements. The developed analytical methodology involved sample digestion under pressure inside a microwave oven with a mixture of HNO3 and H2O2 and inductively coupled plasma-optical emission spectrometry. The method was validated by carrying out the analysis of certified reference materials (NIST 1570a spinach leaves, NCS ZC73016 chicken, and NIST 1568a rice flour) and using recovery experiments. Repeatability was verified by analyzing replicate samples. Twenty-six elements were studied, 12 of which—aluminum, barium, calcium, co…

0301 basic medicineAdolescentMicrowave ovenchemistry.chemical_element01 natural sciencesAnalytical Chemistry03 medical and health sciencesLimit of DetectionHumansEnvironmental ChemistryFood scienceChildMicrowavesPharmacologyMineralsStrontium030109 nutrition & dieteticsChemistryMagnesiumFrench friesSpectrum Analysis010401 analytical chemistryBariumHydrogen PeroxideRepeatabilityFood AnalysisTrace Elements0104 chemical sciencesCertified reference materialsMetalsChild PreschoolCalibrationFast FoodsAgronomy and Crop ScienceFood AnalysisFood ScienceJournal of AOAC INTERNATIONAL
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Raman Spectroscopic Measurements of Dermal Carotenoids in Breast Cancer Operated Patients Provide Evidence for the Positive Impact of a Dietary Regim…

2015

Dermal carotenoids are a feasible marker of the body antioxidative network and may reveal a moderate to severe imbalance of the redox status, thereby providing indication of individual oxidative stress. In this work noninvasive Resonance Raman Spectroscopy (RRS) measurements of skin carotenoids (skin carotenoid score (SCS)) were used to provide indications of individual oxidative stress, each year for five years, in 71 breast cancer (BC) patients at high risk of recurrence. Patients’ SCS has been correlated with parameters relevant to BC risk, waist circumference (WC), and body mass index (BMI), in the aim of monitoring the effect of a dietary regimen intended to positively affect BC risk f…

0301 basic medicineAgingmedicine.medical_specialtyPathologyWaistTime FactorsArticle SubjectBreast Neoplasmsmedicine.disease_causeSpectrum Analysis RamanBiochemistryGastroenterology03 medical and health scienceschemistry.chemical_compound0302 clinical medicineBreast cancerInternal medicineVegetablesmedicineantioxidants skin carotenoids oxidative stress breast cancer Raman spectroscopyHumanslcsh:QH573-671Carotenoidchemistry.chemical_classification030109 nutrition & dieteticsAnthropometryintegumentary systembusiness.industrylcsh:Cytologyfood and beveragesCell BiologyGeneral MedicineAnthropometrymedicine.diseasePrognosisCarotenoidsLycopeneDietOxidative Stresschemistry030220 oncology & carcinogenesisFruitFemalebusinessDietary regimenBody mass indexOxidative stressResearch ArticleOxidative Medicine and Cellular Longevity
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Trifluoroethanol modulates α-synuclein amyloid-like aggregate formation, stability and dissolution

2016

The conversion of proteins into amyloid fibrils and other amyloid-like aggregates is closely connected to the onset of a series of age-related pathologies. Upon changes in environmental conditions, amyloid-like aggregates may also undergo disassembly into oligomeric aggregates, the latter being recognized as key effectors in toxicity. This indicates new possible routes for in vivo accumulation of toxic species. In the light of the recognized implication of α-Synuclein (αSN) in Parkinson's disease, we present an experimental study on supramolecular assembly of αSN with a focus on stability and disassembly paths of such supramolecular aggregate species. Using spectroscopic techniques, two-pho…

0301 basic medicineAmyloidAmyloidBiophysicsSupramolecular chemistryProtein aggregationBiochemistrySupramolecular assembly03 medical and health scienceschemistry.chemical_compoundProtein AggregatesHumansDissolutionAlpha-synucleinProtein Stabilityproteins amyloid fibrils amyloid-like aggregates oligomeric aggregatesSpectrum AnalysisOrganic ChemistryAggregate (data warehouse)TemperatureTrifluoroethanolAmyloid fibrilCrystallography030104 developmental biologychemistryBiophysicsalpha-Synuclein
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DLG4-related synaptopathy: a new rare brain disorder

2021

Contains fulltext : 245031.pdf (Publisher’s version ) (Closed access) PURPOSE: Postsynaptic density protein-95 (PSD-95), encoded by DLG4, regulates excitatory synaptic function in the brain. Here we present the clinical and genetic features of 53 patients (42 previously unpublished) with DLG4 variants. METHODS: The clinical and genetic information were collected through GeneMatcher collaboration. All the individuals were investigated by local clinicians and the gene variants were identified by clinical exome/genome sequencing. RESULTS: The clinical picture was predominated by early onset global developmental delay, intellectual disability, autism spectrum disorder, and attention deficit-hyp…

0301 basic medicineAutism Spectrum Disorder[SDV]Life Sciences [q-bio]030105 genetics & heredityBiology03 medical and health sciencesIntellectual DisabilityIntellectual disabilitymedicineMissense mutationHumansGlobal developmental delayExomeGenetics (clinical)GeneticsBrain DiseasesNeurodevelopmental disorders Donders Center for Medical Neuroscience [Radboudumc 7]Brainmedicine.disease030104 developmental biologyPhenotypeRenal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11]Autism spectrum disorderNeurodevelopmental DisordersSynaptopathyDLG4Postsynaptic densityDisks Large Homolog 4 Protein
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